Dampening the integrated stress response (IRS) in motor neurons may be a valid therapeutic approach in patients with an inherited form of ALS.

A comprehensive genetic analysis of nearly one million people has identified 53 lead variants associated with aging-related frailty.

PacBio develops the Platinum Pedigree benchmark, a new standard for accurate characterization of variation in the human genome.

The fusion of intelligent modeling workflows, PAT, and smart devices will allow biomanufacturers to drastically reduce development costs.

Researchers have elucidated structure-activity relationships underlying a key serotonin receptor shown to regulate mood and cognition.

The new facility will be Asahi Kasei Life Science's fourth spinning plant for hollow-fiber cellulose membrane filters.

Murine study finds eIF2A dependence emerges only after malignant transformation, suggesting a therapeutic window that may spare healthy tissues.

Both psychedelics and non-hallucinogenic analogs are shown to promote cortical neuroplasticity by activating the serotonin 2A receptor.

The primary safety risks associated with gene therapy include immune reactions and off-target effects in unintended organs, ...

Targeted rewriting of the epigenome promises to overcome several challenges in direct gene editing in patient therapies.

From new payload linkers to artificial intelligence partnerships, advances in ADC pipelines push forward selective cancer therapies that minimize side effects.

Novel sponge developed by Takara Bio USA enables effective preparation of T cells for CAR T-cell therapy research from primary PBMC samples.