The Buffalo Bills have announced the team will play its first regular season game at the new Highmark Stadium Week 2 against ...

The Buffalo Bills announced that they will play their first game at the new Highmark Stadium against the Detroit Lions during ...

The Buffalo Bills vs Detroit Lions on Amazon Prime Video for Highmark Stadium home opener ...

The Buffalo Bills will host the Detroit Lions in the first game at Buffalo's new Highmark Stadium. Here's when: ...

Highmark Stadium will officially open its doors as the Bills' new home when they face the Lions on Thursday Night Football in Week 2 on Sept. 17.

First came the rumor Monday night, and then came the somewhat surprising confirmation, straight from the Buffalo Bills. The ...

The Detroit Lions will be the first opponent to square off against the Buffalo Bills in brand new Highmark Stadium.

After months of anticipation, we now know who the Buffalo Bills will play in the first game at the new Highmark Stadium. The ...

The Buffalo Bills will open a new chapter for the franchise in Week 2 when they host the Detroit Lions in the first ...

Normally, the topic of the Bills' first home game wouldn't be a big deal. But this won't be your typical season in Orchard Park.

The Buffalo Bills welcome the Detroit Lions for their home opener in Week 2 on Thursday Night Football. Shop your tickets now ...