A protein naturally made in the body reduces inflammation and pain after surgery, according to a new preclinical study from investigators at the University of Alabama at Birmingham. Published in ...
The company joins a group of degrader ADC (or DAC) developers that includes Bristol Myers Squibb and Pfizer.
An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers.
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...
RNA-binding proteins (RBPs) play critical roles in numerous biological processes because they regulate RNA function by directly interacting with RNA molecules. In recent years, researchers have ...
TEL AVIV, Israel, Sept. 25, 2025 (GLOBE NEWSWIRE) -- SciSparc Ltd. (Nasdaq: SPRC) (the "Company" or "SciSparc"), a specialty clinical-stage pharmaceutical company focusing on the development of ...
Whereas the chemical libraries contain millions of drug compounds, the vast majority of them do not have structures to crystallized targets and is therefore impossible to characterize their binding to ...
Abstract: To accelerate drug discovery, especially during high-throughput screening, accurate estimation of drug-target binding affinity (DTA) is essential. Existing deep learning models often fail to ...