The Lancet

Bedside model-informed precision dosing of vancomycin in severely ill neonates and children in Belgium (the BENEFICIAL trial): a multicentre, randomised controlled trial

iPediatric Intensive Care Unit, Department of Intensive Care Medicine, Ghent University Hospital & Faculty of Medicine and Health Sciences, Department of Basic and Applied Medical Sciences, Ghent ...
Pharm Exec

Bringing the Bayesian Method to Clinical Trials: Q&A with Dr. Stacy Lindborg

Bayesian trials formally integrate prior evidence with accruing data to yield posterior probabilities, supporting interim learning, adaptive modifications, and direct predictive futility/efficacy ...
RAPS

This Week at FDA: Reactions to FDA’s Bayesian methods guidance, GDUFA science report, and more

Welcome to another installment of This Week at FDA, your weekly source for updates – big and small – on FDA, drug, and medical device regulation and what we’re reading from around the web. This week, ...
RAPS

Industry asks FDA to affirm Bayesian methods guidance applies broadly to drugs

Industry groups and drugmakers want the US Food and Drug Administration (FDA) to explicitly clarify that Bayesian statistical methods can be used for products beyond those intended for children and ...
InfoQ

Google Researchers Propose Bayesian Teaching Method for Large Language Models

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Dany Lepage discusses the architectural ...
Medscape

FDA Changes Drug Trial Guidance: Experts Take Sides

The FDA’s new draft guidance on Bayesian methods in clinical trials has been hailed by some as a breakthrough that could speed drug development. But statisticians and researchers are divided on ...
EurekAlert!

Bayesian neural network evaluation method on the neutron-induced fission product yields of Thorium-232

The training error decreases with increasing neuron count and plateaus beyond 28 neurons per hidden layer. For the two-hidden-layer network, error stabilization is ...
Scientific Research Publishing

Khodabandehloo, N., Fourodi, A. and Jenabi, A. (2019) Vancomycin Dosing in Low-Flux Hemodialysis; Is Adjustment of Drug Dosage Necessary? Journal of Renal Injury Prevention, 8 ...

ABSTRACT: Aim: The aim of the study was to investigate the efficacy of vancomycin, when administered at a specific dose before the end of the dialysis session, in achieving therapeutic serum levels ...
Search Engine Land

How Bayesian testing lets Google measure incrementality with $5,000

Incrementality testing in Google Ads is suddenly within reach for far more advertisers than before. Google has lowered the barriers to running these tests, making lift measurement possible even ...
IEEE

Improving Vancomycin Through Level Prediction with Machine Learning: A Comparative Study of Feature Selection and Model Performance

Abstract: Vancomycin is a critical antibiotic used to treat methicillin-resistant Staphylococcus aureus (MRSA) infections, but its narrow therapeutic window necessitates precise dosing to avoid ...
Monthly Prescribing Reference

Tyzavan, a Ready-to-Infuse Vancomycin Formulation, Now Available

Tyzavan is supplied as a single-dose bag in 7 presentations allowing for dosing flexibility. Tyzavan ™ (vancomycin injection), a ready-to-infuse, room temperature stable formulation of vancomycin, is ...