San Francisco 49ers quarterback Brock Purdy will return to action against the Arizona Cardinals on Sunday after a six-week injury absence.

Arizona Cardinals TE Trey McBride was flagged for an unsportsmanlike conduct penalty during Week 11’s contest against the San Francisco 49ers. Replay of his catch and tackle showed all he did was ...

San Francisco 49ers defensive coordinator Robert Saleh and offensive coordinator Klay Kubiak detailed the team's progress in ...

San Francisco 49ers head coach Kyle Shanahan discussed the latest on player recoveries and the challenge of adjusting to ...

The San Francisco 49ers have had a relatively strong start to their season, going 4-2 and but things may start to get more challenging now that linebacker Fred Warner is out for the season with a ...

Fox Sports NFL analyst Tom Brady had a wild reaction to Matthew Stafford's no-look touchdown pass in the Rams vs 49ers game.

Rise of the 49ers premieres on Feb. 1 at 9 p.m. ET with back-to-back episodes on AMC. The final two episodes will debut on ...

From quarterback Matthew Stafford's pregame huddle to coaches celebrating players' touchdowns, relive the Los Angeles Rams' Week 10 win over the San Francisco 49ers at Levi's Stadium.