President Donald Trump is issuing a stark warning to Iran against retaliating against U.S. targets in the Middle East while also predicting Israel and Iran would “soon” make a deal to end their escalating conflict.

By Michael Martina and Katharine Jackson WASHINGTON (Reuters) -Regime change in Iran could be a result of Israel's military attacks on the country, Israeli Prime Minister Benjamin Netanyahu told Fox News on Sunday,

Israel and Iran have opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday on Tehran.

The "America First" president praised his foreign policy record on Sunday while urging a deal between Iran and Israel amid escalating strikes.

Israel targeted Iran’s Defense Ministry headquarters in Tehran and sites it alleged were associated with Iran’s nuclear program, while Iranian missiles evaded Israeli air defenses and slammed into buildings deep inside Israel.

DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

Israel launched a wave of unprecedented strikes on Iran shortly before sunrise Friday morning, hitting key sites in the nation’s nuclear program.