Researchers have identified modes of Sox9 action during cartilage formation by analyzing big data on Sox9 location, chromatin state, and gene expression over the whole mouse genome. This finding will ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

Researchers have shown how gene mutations may cause common forms of cartilage tumors. In a new study, they have revealed that mutations in the isocitrate dehydrogenase (IDH) gene contribute to the ...

Osteochondral defects, often caused by injury or various pathologies, typically lead to the onset of osteoarthritis, and may ultimately result in the comprehensive degradation of the joint and ...

Cartilage is largely composed of a single type of cells, called chondrocytes and various types of extracellular matrix proteins including highly sulfated macromolecule proteoglycans, small ...

Expedition 74 crew members aboard the International Space Station are 3D-printing viable human cartilage tissues inside the ...

A recent article in Engineering describes the development of a protein-based nanocomposite hydrogel designed to deliver two therapeutic agents—dexamethasone (Dex) and kartogenin (KGN)—to support ...

DURHAM, N.C. - Duke Medicine researchers have shown how gene mutations may cause common forms of cartilage tumors. In a study published in the Feb. 16, 2015, issue of the Proceedings of the National ...