A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...
Chemical structure of imatinib, a precision cancer drug containing an amide bond. Xiaoguang Lei and his team used their engineered enzyme to streamline the synthesis of imatinib, a landmark cancer ...
A catalyst that effectively converts amides to amines at low temperature under low hydrogen pressure has been demonstrated by a team of researchers. Amines are vital in nature; for example, amino ...
DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...
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