Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for developing effective treatments.

Signalling pathways are used to transmit information within cells. These complex networks of molecules control critical cellular functions such as growth, division, cell death and, indeed, mitophagy.

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain ...

Psychiatric disorders, including depression, schizophrenia, anxiety, and bipolar disorder, are increasingly recognized as ...

BACKGROUND: Whereas antiphospholipid syndrome (APS) is best known for increasing the risk of macrovascular thrombosis, APS vasculopathy is characterized by the abnormal proliferation of endothelial ...

A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the ...

Calibrating Chimeric Antigen Receptor (CAR) Signaling to Improve CAR T-Cell Therapies The following represents disclosure information provided by authors of this manuscript. All relationships are ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical ...

Protective mechanism: Biofilm formation Bacteria respond to this danger signal by producing a small signaling molecule known as c-di-GMP, which triggers biofilm formation.