Dysregulated cell signaling underlies various diseases, emphasizing the importance of understanding these pathways for developing effective treatments.

Signalling pathways are used to transmit information within cells. These complex networks of molecules control critical cellular functions such as growth, division, cell death and, indeed, mitophagy.

Psychiatric disorders, including depression, schizophrenia, anxiety, and bipolar disorder, are increasingly recognized as ...

Restoration of the integrity of TCR signaling by allogeneic hematopoietic-cell transplantation led to the resolution of all HPV-related diseases, thereby revealing a direct role of β-HPV in skin ...

Calibrating Chimeric Antigen Receptor (CAR) Signaling to Improve CAR T-Cell Therapies The following represents disclosure information provided by authors of this manuscript. All relationships are ...

A Northwestern Medicine study has uncovered new insights that may aid in understanding and potentially treating one of the most common and aggressive forms of non-Hodgkin lymphoma, according to ...

Protective mechanism: Biofilm formation Bacteria respond to this danger signal by producing a small signaling molecule known as c-di-GMP, which triggers biofilm formation.

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical ...

Drink your milk and you will have strong bones and healthy teeth'. We’ve all heard this advice. It's supposed to help us meet ...