Epigenetic regulation involves several key mechanisms, including DNA methylation, histone modification, and RNA-mediated processes.

Based on this, Peng and Qin further comprehensively summarized the epigenetic regulation mechanism of oxidative stress on tumor metastasis, from DNA methylation, histone modification, ncRNAs and ...

Histone modifications (acetylation and methylation) are critical in activating and repressing gene transcription. Therefore, the epigenome is the collective epigenetic information present in a cell.

Similar to other epigenetic mechanisms, histone modification plays a role in several disease processes. 18 Researchers have linked abnormal changes in histone modifier enzyme activity to cancer ...

These findings provide crucial insights into the mechanism that regulates parental histone recycling by the replisome to ensure the faithful propagation of epigenetic information at each cell ...

A recent review in eGastroenterology explores how key epigenetic changes—including DNA methylation, histone modifications, and noncoding RNAs—drive the development and progression of ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

Epigenetics plays a vital role in cancer research in understanding the difference in nuclear organization, DNA methylation, and histone modification patterns between cancer cells and normal cells.

The packaging of DNA within chromosomes, the orderly replication and distribution of chromosomes, the maintenance of genomic integrity, and the regulated expression of genes depend upon nucleosomal ...

Recent advances in epigenetics research provide more clues as to why identical twins are different and offer ways to treat ...