The U.S. and Israel have launched major attacks on Iran, whose state media say Supreme Leader Ayatollah Ali Khamenei is dead.

U.S. allies and adversaries responded to the joint attacks by the U.S. and Israel on Iran with concern over the risks of a new war in the Middle East.

The United States and Israel have launched a major attack on Iran, which President Donald Trump said would lay waste to the country’s military, obliterate its nuclear program, and could even topple its regime.

The United States and Israel have clashed with Iran at an emergency meeting of the U.N. Security Council, where the U.N. chief and many countries urged a halt to their attacks and a return to negotiations.

Video footage shows the Israel Defense Forces striking two F-4 and F-5 fighters before they took off from an airport in western Iran.

Israeli airstrikes hit 500 Iranian targets including missile launchers and defense systems, severely degrading Iran's offensive military capabilities.

At Federal Plaza, demonstrators expressed concern following the military operation in Iran that killed the country's supreme leader and the impact it may have going forward.

An enormous explosion rocked Iran's capital Sunday as the Israeli military said it was targeting the heart of the city.