We're one day away from the US Open main draw getting underway and all of the top players have arrived at Flushing Meadows to conduct their media obligations. Yesterday we heard from Emma Raducanu, Novak Djokovic, Coco Gauff and a host of other icons.

Carlos Alcaraz and Novak Djokovic will face potential difficult American opponents when they begin their quest for another U.S. Open title.

Here are the latest odds from FanDuel Sportsbook on who will win the 2025 U.S. Open men's and women's singles titles

They'll still play the full U.S. Open starting Sunday in New York, but it might save some time to skip ahead to the men's final on Sept. 7.

Big names fell early and unexpected teams broke through to steal the spotlight on Day 1 of U.S. Open mixed doubles play, headlining an electric opener packed with upsets and standout performances.

Sabalenka is currently +285 to repeat as champion, second only to Iga Swiatek at +240. Sinner, meanwhile is favored to repeat at +110, slightly ahead of rival Carlos Alcaraz at +175. With some of those odds in mind, let's take a look at some of the best betting options to consider in both the men's and women's tournaments this year in New York.