Stem cell-derived pancreatic islets are being studied as a rich transplantable source for insulin production, a therapeutic for type 1 diabetes that overcomes the need to obtain islet cells from ...

Pancreatic islets are mini-organs that make and release insulin and several other peptide hormones to control our glucose levels. Although various studies have previously looked at how pancreatic ...

Islets, found in the pancreas, are clusters of insulin-secreting and other cells enmeshed in tiny, specialized blood vessels. The insulin cells are killed by an autoimmune process in type 1 diabetes, ...

All 12 patients in study (100%) achieved insulin independence, producing their own insulin and no longer requiring exogenous insulin therapy to ...

Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...

Advancing CNTY-813 as a potential functional cure in Type 1 DiabetesCNTY-813 iPSC-derived islet replacement therapy demonstrates durable in-vivo ...

All tissue samples were obtained from the Department of Pathology, University Hospital of Zürich, Zürich, Switzerland. Patients with pancreatitis, lymphoma, and systemic infection and who were on ...

An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem ...