New immunotherapy targets for glioblastoma identified by mapping cell interactions

Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and ...
EurekAlert!

Neutrophil extracellular traps license macrophage production of chemokines to facilitate CD8+ T cell infiltration in obstruction-induced renal fibrosis

NETs promote macrophage expression of T-cell chemokines and subsequently facilitate cytotoxic CD8+ T cell infiltration and granzyme B production, which drives kidney fibrosis in obstructive ...

This new understanding of T cell receptors may improve cancer immunotherapies

T cell immunotherapies are on the cutting-edge of cancer treatments, but a full understanding of how they work has been ...
STAT

Miriam Merad’s 20-year quest to understand one cell is starting to rewrite the rules of cancer immunotherapy

Angus Chen covers all issues broadly related to cancer including drugs, policy, science, and equity. He joined STAT in 2021 after covering health and science at NPR and NPR affiliate stations. His ...
Case Western Reserve University

James M. Anderson, MD, PhD

Foreign body reaction to biomaterials, James M. Anderson, Analiz Rodriguez, and David T. Chang, Seminars in Immunology, 2008;20(2):86-100. Biodegradation and ...