In 1999, the first human chromosome was sequenced in full thanks to the Human Genome Project. It was a climactic accomplishment for genetic engineering, but it could’ve easily been seen as a Pandora’s ...

The scientists at the center of Splice should have watched a couple of horror movies - that way, they'd know to never go against the moral code and inject human DNA into one of their genetic creations ...

I'm not sure if "Splice" is a great monster movie, but it features a great movie monster. The film revolves around an unsettling chimera, named "Dren" by her creators. Dren is a lethal mix of lovely ...

The Vincenzo Natali-directed Splice opens this weekend with the distinction of being arguably the biggest acquisition to ever emerge from the Sundance Film Festival, based on Dark Castle’s $35 million ...

Steeped in geek-dom and centered with science fiction, Splice is a horror film where the horror comes last. The moral dilemma of what Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) are doing ...

The long shadow of the recession may still be darkening the land, but one thing that’s seeing a resurgence at the multiplex this summer is the mad-scientist industry. First up was Teutonically evil Dr ...

If you caught Splice this weekend, you might have a few questions about the movie’s shocking twists. Director Vincent Natali broke down a few questions we had and explained tributes to other films – ...

Dark, sleek, funny and creepily infectious, the genetic-engineering horror-comedy “Splice” is a dynamic comeback vehicle for Canadian genre director Vincenzo Natali, who made a splash a few years ago ...

Vincenzo Natali nearly died while making his first movie, “Cube.” Made on a shoestring budget, his 1997 psychological horror only had one practical set — a huge, boobie-trap-filled cuboid prison to ...

Director Vincenzo Natali might not be a familiar name to you yet, but just wait. The man behind the small, mind-bending films like Cube and Nothing is set to release his next, called Splice, for which ...

Matt Goldberg has been an editor with Collider since 2007. As the site's Chief Film Critic, he has authored hundreds of reviews and covered major film festivals including the Toronto International ...