The San Francisco 49ers got some unfortunate injury news Sunday morning, with an impact that will be felt all the way up in week five.

The San Francisco 49ers asserted themselves as contenders in the NFC during their season opener. San Francisco dominated Los ...

Of those three clubs, the Seattle Seahawks and Los Angeles Rams were the most popular picks from pundits to win the Super Bowl this February. But all three of those clubs have already played a game.

The San Francisco 49ers will reportedly be without promising rookie wide receiver De'Zhaun Stribling for at least a month.

SANTA CLARA, Calif. -- A pair of vintage Russell Wilson plays helped the Seattle Seahawks extend their lead against the San Francisco 49ers on Sunday. After scrambling for a 16-yard touchdown run, ...

The NFL openers resulted in wild outcomes for the Seattle Seahawks, Los Angeles Rams and San Francisco 49ers, the three NFC ...

The Rams have the offense, the Seahawks have the defense, and the 49ers have zero room for error in a loaded NFC West.