The clinical use of sodium glucose co-transporter 2 inhibitors (SGLT2) represents a recent advance in the treatment of diabetes. Accumulating evidence suggests that these drugs may reduce the risk for ...

MUNICH — A study evaluating the occurrence of CV, cerebrovascular and renal events in elderly patients with hyperuricemia showed that lowering serum uric acid levels with febuxostat had a greater ...

The PREDIAN trial investigated the renoprotective effects of pentoxifylline, in addition to renin–angiotensin system blockade, in patients with type 2 diabetes mellitus and chronic kidney disease.

Background: Previously the angiotensin II receptor blocker Irbesartan has been demonstrated to reduce the risk for progression from microalbuminuria to macroalbuminuria in type 2 diabetic patients.

Munich, Germany - Final results of a head-to-head comparison of the ACE inhibitor enalapril and the angiotensin receptor blocker (ARB) telmisartan show the agents are comparably renoprotective in ...

Renal progenitor cells derived from human iPS cells were shown to have therapeutic effects when transplanted into acute kidney injury model mice. The transplants resulted in a significant reduction of ...

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli. The ...

Increases in the proportion of red blood cells mediates the reduction in renal risks associated with SGLT2 inhibitor therapy in patients with type 2 diabetes and cardiovascular disease, a study found.

Lubiprostone preserved renal function in stage IIIb-IV CKD patients over 24 weeks without altering uremic toxin levels, suggesting a novel renoprotective mechanism. The trial demonstrated ...

Adding aliskiren to losartan reduced albuminuria in hypertensive patients with diabetic nephropath. Aliskiren, an oral direct renin inhibitor, may have renoprotective effects that are independent of ...

Background. Acute kidney injury independently predicts mortality in falciparum malaria. It is unknown whether acetaminophen’s capacity to inhibit plasma hemoglobin-mediated oxidation is renoprotective ...