Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is ...

Researchers have developed a new artificial intelligence (AI) model that can more accurately predict how proteins interact with one another—an advancement that could accelerate drug discovery and ...

Researchers have developed a type of peptides that can enter cells and block protein interactions considered difficult to ...

In an intricate dance, missteps or errant gestures between two partners can disturb the entire ensemble. Such is the molecular dance that is life. Here, the partners that need to hit their cues, ...

Scientists have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication. The computational tool is ...

A new method screens large libraries of synthetic cyclic peptides to identify compounds that can enter cells for therapeutic effect.

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational design ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat ...