Mitotically active embryonic reproductive cells, the primordial germ cells (PGCs), are an ideal cell type for cryopreserving functional reproductive cells for avian species. Their low number in the ...

Germ cell development begins with the specification of primordial germ cells (PGCs) in the early embryo, which subsequently migrate to the developing gonads and undergo extensive epigenetic ...

Although assisted reproductive technologies (ARTs), such as in vitro fertilization (IVF), have had a tremendous impact on treating certain forms of infertility—not all forms of infertility can be ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Researchers at the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have shown for the first time that, before they can start developing into egg and sperm cells, the embryonic ...

(A) Germ-cell-removed turquoise killifish and their gonads. (B) Lifespan of germ-cell-removed animals. Credit: 2024 Ishitani et al., Sex-dependent regulation of vertebrate somatic growth and aging by ...