Gene delivery to differentiated hepatocytes is notoriously difficult. Hepatocytes plated on collagen-coated dishes and maintained in dimethyl sulfoxide (DMSO)-supplemented medium acquire paracellular ...
The transmembrane protein claudin-2 mediates paracellular sodium reabsorption in the proximal tubule, but given the versatility of transcellular epithelial transport, the paracellular pathway seems ...