While Isner has only beaten Nadal once in eight previous meetings — and that lone win came indoors — the big-serving American pushed Nadal to five sets at the 2011 French Open.

Up next for Isner will be his 53rd Grand Slam tournament at the French Open, which starts May 22. First, though, he'll take his family for a little break on the Spanish island of Mallorca.

While Isner has only beaten Nadal once in eight previous meetings – and that lone win came indoors – the big-serving American pushed Nadal to five sets at the 2011 French Open. ”This is a very cool ...

So maybe I can try to take advantage of that.” The 6-foot-10 Isner certainly looked confident in a 6-4, 6-3 first-round win over Miami Open semifinalist Francisco Cerundolo.