The 49ers are 4.5-point favorites, according to the latest Browns vs. 49ers odds. The over/under for total points scored is 36.5. Before making any Browns vs. 49ers picks, make sure you check out the NFL picks from the SportsLine Projection Model.

Two-time top-five Westgate SuperContest finisher “Dr. Alan” Dumond analyzes every NFL Week 13 Sunday and Monday game and makes predictions for each matchup.

Yahoo Sports NFL analyst Nate Tice and NFL writer Charles McDonald react to the Tampa Bay quarterback’s sprained shoulder he suffered in Sunday night’s loss to the Los Angeles Rams. Check out the full conversation on “Football 301” - and subscribe on Apple Podcasts, Spotify, YouTube or wherever you listen.

There's underdog value on Thanksgiving. That extends to Sunday with a pair of NFL also-rans defending their home turf.

The public has finally — finally! — appeared to turn its back on Kansas City. Patrick Everson breaks down the betting ahead of NFL Week 12.

Stafford is on a historic tear, with 25 touchdowns and no interceptions since Week 3. He leads the NFL with 30 touchdown passes. The Rams have the best record in the NFC, and being the quarterback on a No. 1 seed has been the winning formula for MVP voters for many years.

NFL Week 13 betting spreads, lines, point totals for every game on NFL Week 13 schedule, with odds for favorites and underdogs in each NFL matchup.

The bet365 bonus code WEEK365 will unlock access to a $150 bonus for NFL Week 13 matchups played November 30, 2025.