Protein aggregation is often observed in various biological processes, characterized by the accumulation of improperly processed or misfolded proteins within cells 1,2. This aberrant occurrence is ...
The NF-κB pathway plays a critical role in mediating the innate immune response downstream of activated immune receptors such as the TNFαR. Activation of this pathway is induced by several ubiquitin ...
Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...
The diagram depicts negative feedback mechanisms via IκB proteins and A20 in the canonical pathway, and IKKα onto NIK in the non-canonical pathway. There are cross-talk mechanisms such as NIK ...
Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...
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