In the developing brain, neurons must navigate through complex and often crowded tissue to reach their final destinations—this process is crucial for proper brain formation and function. Similar to ...

The structure and functions of the tip of migrating neurons remain elusive. A research group has found that the PTPσ-expressing growth cone senses the extracellular matrix and drives neuronal ...

Collective time-lapse images of a migrating neuron (left) and an elongating axon (right) from super-resolution microscopy. Growth cones at the tips of the neurons are extended while the cell body ...

Researchers from the University of New Hampshire looked at the developmental process of the cerebral cortex—the outermost layer of the brain—and examined how neurons, or nerve cells, refine their ...

The assembly of a healthy brain requires new cells to travel incredibly long distances to arrive at their correct final destinations. A recent laboratory mouse study reveals that dopamine receptors ...

The entorhinal cortex is one of the most interconnected brain regions and is essential for spatial navigation and memory formation 1. These abilities mature throughout childhood, and have generally ...

Neuronal precursors from a particular region of the ventral forebrain--the medial ganglionic eminence (MGE)--are capable of migrating extensively in both the embryonic and adult brain and ...

Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to ...

Using microfluidic devices mimicking the crowded spaces in the developing brain, researchers gained novel insights into distinct modes of locomotion found in neurons. In the developing brain, neurons ...