Scientists at Van Andel Research Institute and Rockefeller University have successfully described a crucial structure involved in DNA replication, placing another piece in the puzzle of how life ...

This movie shows the helicase protein complex from all angles, and reveals how its shape changes back and forth between two forms. The research team hypothesizes that the rocking action of this ...

SWI2/SNF2 chromatin-remodeling proteins mediate the mobilization of nucleosomes and other DNA-associated proteins. SWI2/SNF2 proteins contain sequence motifs characteristic of SF2 helicases but do not ...

A new crystal structure reveals the path taken by single-stranded (ss) DNA through the central channel of a hexameric helicase. The path resembles a spiral staircase and provides an answer to the ...

Scientists have solved the structure of the Zika virus helicase, which is a key target for antiviral development. A team led by researchers from Tianjin University (P.R. China) has solved the ...

These are two images showing the structure of the helicase protein complex from above. (a) A surface-rendered three-dimensional electron density map as obtained by cryo-EM. (b) A computer-generated ...

Scientists have successfully described a crucial structure involved in DNA replication, placing another piece in the puzzle of how life propagates. Scientists at Van Andel Research Institute and ...

A team led by researchers from Tianjin University (P.R. China) has solved the structure of the Zika virus helicase, which is a key target for antiviral development. The research is published in ...