One of the most familiar and widely used methods for quantifying cell proliferation is the measurement of tritiated thymidine ([3 H]-thymidine) incorporation. Cells incorporate the labeled DNA ...

CDK4/6 inhibitors are effective at treating advanced HR+ /HER2- breast cancer, however biomarkers that can predict response are urgently needed. We demonstrate here that previous large-scale screens ...

Lung adenocarcinoma (LUAD) is the most prominent subtype of non-small cell lung cancer characterized by high morbidity and mortality. While integrins are known regulators of tumor progression, most ...

The primary causes of disability and mortality in the US are chronic diseases such as cancer, neurodegenerative disorders, cardiovascular disease, obesity, arthritis, and diabetes. The increase in ...