If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

The factors involved in the removal of RNA primers during plastid DNA (ptDNA) replication have been unclear. We now identify a plastid-localized 5′–3′ exonuclease (PEN1) that mediates the removal of ...

Efficient and accurate DNA replication is essential for the preservation and transmission of the genetic information of all living organisms, from bacteria to humans. However, DNA replication shares ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages ...

"DNA guides are far cheaper and easier to manufacture than RNA guides, and they are far more stable," Jain said. "While RNA molecules degrade quickly, DNA can remain intact for long periods." Together ...

A DNA-guided CRISPR platform could make RNA detection and control more stable, scalable, and precise, opening new routes for diagnostics, transcriptome engineering, and future therapeutic research.

CRISPR’s rise from obscure bacterial defense system to molecular scalpel has always hinged on one small component: the guide RNA. For years, that guide RNA—meticulously designed, modified, and ...

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth—a key process in the origin of life. Scientists ...

New method uses DNA barcodes for high throughput RNA and protein detection in deep tissue. ScienceDaily. Retrieved June 18, 2026 from www.sciencedaily.com / releases / 2025 / 03 / 250311121315.htm ...

Caltech researchers have identified a novel chemical reaction that could explain the formation of the building blocks of DNA ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...