A preclinical study has reported that simultaneous inhibition of cyclin-dependent kinases 2 and 4/6 produced durable tumour ...
The C-Jun N-Terminal Kinase (JNK) signalling pathway plays a pivotal role in regulating cellular responses to stress and damage. As a member of the mitogen-activated protein kinase (MAPK) family, JNK ...
Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...
Stressed brain cells can survive longer by slowing sugar use, revealing a short-term protective response that later turns ...
The mitogen-activated protein kinase (MAPK) pathway integrates growth factor signaling through extracellular signal-regulated kinase (ERK) to control cell proliferation. To study ERK dynamics, many ...
AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream activation by the kinase LKB1 is well recognized, the ...
EMA recommends Kygevvi for rare thymidine kinase 2 deficiency. It is the first authorized treatment for this disease.
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