Pluripotent mouse embryonic stem cells (ESCs) can differentiate to all germ layers and serve as an in vitro model of embryonic development. To better understand the differentiation paths traversed by ...

In primates, abnormalities during gastrulation and early organogenesis lead to a high incidence of early abortion and developmental defects at birth 8. Thus, elucidating the cellular and molecular ...

When planning a trip, it's rare that you don't have a choice of route. One may be more direct, another more scenic; but regardless of the time or route taken, the destination is the same. This concept ...

For the first time, stem cells typically considered restricted to forming body tissues spontaneously formed a yolk-sac-like structure in a model of the human embryo. Stem cell models of human embryos ...