Upon evaluation of previous case reports, it is evident that careful consideration should be taken upon prescribing and monitoring topiramate therapy. Practitioners should obtain a detailed history ...

Sodium is the primary cation. Chloride and bicarbonate are the primary anions. The anion gap is the numeric result of subtracting the sums of the chloride and bicarbonate concentrations from that of ...

A Japanese registry has identified a blind spot in the routine care of patients with chronic kidney disease (CKD). Serum bicarbonate levels are rarely measured, leaving metabolic acidosis largely ...

Acid-base disorders are frequent in emergency and critical care, but many patients present with more than one imbalance at once. Clinicians rely on structured methods like anion gap correction and ...

Sodium bicarbonate is an antacid medication that may help treat metabolic acidosis in people with kidney disease. If a person has kidney disease, it may cause them to develop metabolic acidosis. This ...