Cellular motility is orchestrated by the dynamic assembly and disassembly of actin filaments coupled to the force-generating activity of myosin motors. Globular actin (G-actin) polymerises into ...

Chara corallina myosin XI (CcXI) drives the movement of actin filaments, which spontaneously form ring-like structures due to a slight curvature that leads to polar alignment. Living cells are highly ...

Our skin and mucous membranes are protected by epithelial cells. This 'barrier' tissue performs its function thanks to specialized structures called 'junctions'. They ensure cell cohesion and regulate ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

Our skin and mucous membranes are protected by epithelial cells. This barrier tissue performs its function thanks to specialized structures called junctions. They ensure cell cohesion and regulate ...

A team of biophysicists from the University of Massachusetts Amherst and Penn State College of Medicine set out to tackle the long-standing question about the nature of force generation by myosin, the ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...

From next-generation medications to groundbreaking gene therapies and nonsurgical procedures, explore the pipeline of ...

Scientists at the University of Leeds have used cryo-electron microscopy to reveal how platelet myosin stays inactive until needed for blood clotting. The study identified structural 'off-switch' ...