Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...

The tendency of actin to polymerize initially thwarted crystal production. Holmes and colleagues overcame this by complexing rabbit skeletal actin with DNase I, thereby preventing polymerization and ...

Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists from the Perelman ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...

The first crystal structure of an actin molecule not associated with another protein has been solved. Remarkably, the most variable part of actin's structure is also the most conserved part of its ...

Scientists at Université de Montréal's Institute for Research in Immunology and Cancer (IRIC) have identified a dynamic structure that forms a network on the surface of epithelial cells. Led by ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists have now taken a ...