Figure 2: Human alpha cells express vAChT and ChAT. Figure 3: Isolated human islets secrete acetylcholine (ACh) in response to alpha cell–specific stimuli. We further used the biosensor assay to ...

Attention is a rich and complex psychological and neurobiological construct. In both non-human 1,2,3,4 and human primates 7, researchers have investigated a wealth of paradigms tapping visual ...

In 1921, Otto Loewi woke from a dream with the idea for an experiment that proved nerves communicate using chemicals, not just electricity. By showing that stimulating one frog’s heart released a ...

Acetylcholine (ACh) rechallenge may be a novel method to improve detection of coexisting coronary spasm endotypes, and at the same time, assess the treatment response to nitrate-based therapies, a new ...

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce ...

Memopezil is at the center of a rapidly growing conversation about cognitive health in 2026, as consumer interest in brain support has reached an all-time high, with search volume for terms like ...

More than 60% of complement inhibitor–naive patients with acetylcholine receptor–positive generalized myasthenia gravis (MG) in diverse clinical populations had a clinically meaningful reduction in MG ...

Karolinska Institutet researchers identified dopamine-acetylcholine disruptions in the basal ganglia as key contributors to autism-related behavioral inflexibility. Using advanced techniques like ...

Acetylcholine (ACh) is a neuromodulator with a central role in aversive learning - rapid conditioning to unpleasant smell, taste, or touch. These learning functions play out in cells called D2 ...