Research conducted at the National Cancer Research Centre (CNIO) has revealed an unexpected behavior observed in a protein ...
New findings show that a fusion protein in cancer can reuse ADP as fuel alongside ATP to self-activate more quickly.
Researchers at Spain’s National Cancer Research Centre have discovered that the CCDC6-RET fusion protein, linked to lung and thyroid cancers, can self-activate and use both ATP and ADP as energy ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
Researchers at Spain’s National Cancer Research Centre have found that CCDC6-RET, a fusion protein linked to lung and thyroid cancers, can activate itself far faster than normal proteins and draw ...