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Predictions, picks and odds for NFL Week 13 game

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Who is favored to win in Indianapolis Colts vs. Houston Texans? NFL predictions, picks in Week 13

The Indianapolis Colts ' AFC South lead has narrowed in recent weeks as they host a division foe, the Houston Texans.

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Texans vs. Colts Final Score Prediction for NFL Week 13 (Houston's Defense Will Keep Game Close)

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Houston Texans at Indianapolis Colts odds, picks and predictions

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Colts vs. Texans best bets, picks and odds | Week 13 2025

Check out best bets as the Houston Texans (6-5) will attempt to extend a three-game winning streak when they visit the Indianapolis Colts (8-3) on Sunday, November 30, 2025 at Lucas Oil Stadium.

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Texans' C.J. Stroud to return against Colts after concussion recovery

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Texans open as road underdogs vs. Colts in Week 13

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Texans Announce C.J. Stroud Development on Friday

In Stroud's absence, Mills passed for 856 yards and five touchdowns to just one interception, while completing 58% of his passes.

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Pro Picks: Texans will upset the Colts to tighten the race in the AFC South

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C.J. Stroud clears concussion protocol, will start Sunday vs. Colts

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NFL Hands Down Punishment Over Texans Team Captain Azeez Al-Shaair

Houston Texans linebacker Azeez Al-Shaair was on the receiving end of a fine-worthy play that got the league involved.

Last-minute NFL Week 13 picks: Why we're backing Shedeur Sanders, Browns other underdogs to cover

The only thing that's better than Thanksgiving dinner is when you can break open the leftovers. As we gear up for a jam-packed Sunday slate of NFL action, there's no better time to dive into those final pieces of turkey while firing off some last-minute bets in the process.

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How Thursday's NFL results impacted the Houston Texans' playoff standing in AFC

Kansas City and Baltimore each lost to give Houston a temporary boost in the wild-card race. The Chiefs and Ravens are both 6-6, one half game behind Houston (6-5). Baltimore fell out of the AFC North lead with the loss to Cincinnati. Teams listed in order of tiebreakers. The top seed receives a first-round bye.

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Texans at Colts: Predictions, picks and odds for NFL Week 13 game

USA Today's NFL experts make their picks for a Week 13 showdown between the Indianapolis Colts and Houston Texans

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TV broadcast maps for Week 12 of 2025 NFL season

Week 12 of the 2025 NFL season kicked off Thursday with the Houston Texans defeating the Buffalo Bills. But there's still plenty of action to come this weekend.