Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

Mr. Netanyahu said Israel was facing “difficult days, but great days” ahead. He also repeatedly invoked the Holocaust — the annihilation of European Jewry — as a reason not to treat a nuclear Iran lightly. “Together, with God’s help, we will ensure Israel’s eternity,” he said.

Iran once ridiculed Israeli Prime Minister Benjamin Netanyahu as the boy who cried wolf for his constant public warnings about Tehran's nuclear programme, and his repeated threats to shut it down, one way or another.